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Research: Past Research

PRHE has collaborated with scientists and other experts in the field of environmental health on a range of topics that effect human reproduction and development.

Environmental exposures and adverse pregnancy outcomes: a review of the science


  • To better understand the science linking environmental contaminants exposures with adverse pregnancyoutcomes

PI(s): Tracey Woodruff (UCSF); Karen Stillerman (Physicians for Social Responsibility)
Funding:  UCSF, PSR, Marisla Foundation
Publication(s): http://www.ncbi.nlm.nih.gov/pubmed/18836129

International Collaborative on Air Pollution and Pregnancy Outcomes (ICAPPO)


  • Reviews find a likely adverse effect of air pollution on perinatal outcomes, but variation of findings hinders the ability to incorporate the research into policy. ICAPPO was formed to better understand relationships between air pollution and adverse birth outcomes through standardized parallel analyses in datasets from different countries.

PI(s): Tracey Woodruff (UCSF); Jennifer Parker (CDC National Center for Health Statistics)
Funding: Association of Occupational and Environmental Medicine Clinics, University of Washington, Seattle; Center for Occupational and Environmental Health and Fogarty Center, University of California at Los Angeles; Health Effects Institute; Institute of Health and Society, Newcastle University; Program on Reproductive Health and the Environment, National Center of Excellence in Women's Health, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California at San Francisco; School of Forestry and Environmental Studies, Yale University; University of Michigan;  Ewha Womans University, Seoul, South Korea.

Women’s Reproductive Health and the Environment


  • To evaluate the possible role of endocrine-disrupting compounds (EDCs) on female reproductive disorders emphasizing developmental plasticity and the complexity of endocrine-dependent ontogeny of reproductive organs. Declining conception rates and the high incidence of female reproductive disruptions warrant evaluation of the impact of EDCs on female reproductive health.

PI(s): Linda Guidice (UCSF); Lou Guillette (U Florida)

Funding: John Burbank and Alison Carlson, the Barbara Smith Fund, the Johnson Family Foundation, the New York Community Trust, Turner Foundation, Inc

Assessing cumulative burdens of chemical exposure among pregnant women in the United States


  • Expand an existing study based on the National Health and Nutrition Examination Survey (NHANES) to include the development of scientifically and policy based metrics that reflect cumulative exposure to chemicals.
  • Use these metrics to determine whether certain social, demographic or socioeconomic factors are associated with high or low exposure to chemical mixtures.
  • Improve our understanding of real-life exposure scenarios, including the multiplicity of exposures during pregnancy.
  • Contribute to current policy discussions on chemicals policy reform, to regulatory efforts to integrate cumulative exposures into decision-making as well as to epidemiologic research.

PI(s): Tracey Woodruff (UCSF)

Funding: Passport Science Innovation Fund; Pew Charitable Trusts

Publication(s): http://www.ncbi.nlm.nih.gov/pubmed/21233055

PRHE Research

Learn more about PRHE's current research.

PRHE's Policy Work

Learn more about PRHE's current work on environmental exposures and public policy.

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